What is Olaparib used for?
What is Olaparib used for?
Blog Article
Olaparib is a mammalian poly ADP ribose polymerase (PARP) inhibitor. PARP is a protein that plays an important role in helping damaged cells repair themselves.Cancerassociated with BRCA1 or 2 mutations appear to rely on PARP to repair damaged DNA in cancer cells, allowing them to continue dividing. By inhibiting PARP, tumor growth may be slowed or stopped. Olanib 50 mg is effective in inhibiting the activity of BRCA. This is a gene mutation that can appear in patientsovarian cancer. Olaparib will help stop or shrink tumors in people withovarian cancerfinal stage
2. How to use Olaparib
Olanib 150 mg (Olaparib) comes as a tablet. Take the medicine after meals. The tablets should be swallowed whole and should not be chewed, broken, or crushed. If you miss a dose, take your next dose at the regular time.
Recommended dosage:
The recommended dose of olanib 50 mg is 400 mg (8 tablets of 50 mg); Take 4 tablets twice daily, for a total daily dose of 800 mg. Continue treatment until disease progression or until your doctor tells you to stop. To control adverse reactions, your doctor will consider interrupting the treatment dose or reducing the dose.
The recommended dose reduction is 200 mg (4 tablets of 50 mg): Taken orally twice daily, for a total daily dose of 400 mg. The final dose reduction is 100 mg (2 tablets of 50 mg): Taken orally twice daily, for a total daily dose of 200 mg.
3. Storage and processing
This medication should be stored in its original, labeled container, at room temperature and in a dry place (unless otherwise directed by your healthcare provider or pharmacist). Keep the container out of the reach of children and pets.
If a caregiver prepares your dose, they should wear gloves or pour the medicine directly from the container into a cap, small cup, or directly into your hand.
4. Possible side effects of Olaparib
When using the drug, you may experience some of the following side effects:
Nausea or vomiting;
Tired:TiredFatigue is a common feeling during cancer treatment that is not relieved by rest. During cancer treatment and for some time afterward, you may need to adjust your schedule to manage fatigue.
Diarrhea: To limit this side effect, avoid raw fruits, vegetables, whole-grain breads, cereals, and nuts. Soluble fiber is found in some foods and absorbs fluid, which can help reduce diarrhea. Drink 8-10 glasses of non-alcoholic, non-caffeinated fluids each day to prevent dehydration.
Low white blood cell count
Muscle or joint pain/headache and dizziness: If you have these symptoms, tell your doctor.
Kidney toxicity : This medication can cause kidney toxicity, which your doctor will monitor using blood tests to check your creatinine levels. Notify your doctor if you notice decreased urine output, dark urine, blood in your urine, or swelling in your ankles.
Lung problems: Patients may develop pneumonia while taking this medication. Notify your treating physician immediately if you develop any new or worsening symptoms, including difficulty breathing, shortness of breath, cough, or fever.
Secondary Cancer : Secondary cancer is cancer that develops as a result of cancer treatment for another cancer. This is quite rare, but you should be aware of the risk. In most cases, secondary cancers related to chemotherapy are leukemia (leukemia, lymphoma). This can occur many years after treatment. This is often related to repeated treatments or high doses.
Blood clot: This medication may increase your risk of developing a blood clot (DVT or PE). Symptoms may include: swelling, redness, or pain in the extremities, or difficulty breathing. If you experience symptoms of these problems, notify your doctor immediately for prompt treatment.
Fertility problems: Exposure to this medicine can cause birth defects in an unborn baby, so you should not become pregnant or father a child while taking this medicine. You should not breast-feed while taking this medicine or for 1 month after your last dose.
Olaparib is a prescription drug, so before using it, make sure you have consulted your doctor. Hopefully, this article has provided you with useful information about the uses, dosage, and precautions when using Olaparib.
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